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Antibodies

Recombinant NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) Antibody

Product Sizes
100 ug
£671.00
4831-RBM11-P1ABX-100UG
About this Product
SKU:
4831-RBM11-P1ABX
Additional Names:
C-myc purine-binding transcription factor PUF | Histidine protein kinase NDKB | nm23-H2
Application:
Western Blot
translate.label.attr.clone:
NME2/12953R
Clonality:
Monoclonal
Extra Details:
The nm23 gene; a potential suppressor of metastasis; was originally identified by differential hybridization between two murine melanoma sub-lines; one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis; nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans; NDP kinases A and B are identical to two isotypes of human nm23 homologs; namely nm23-H1 and H2; respectively. nm23-H2 is identical in sequence to PuF; a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor.
Host:
Rabbit
Immunogen:
Recombinant full-length human NME2 protein
Isotype:
IgG
Molecular Weight:
17kDa
Research Area:
Immunology
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody