Recombinant NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) Antibody
Product Sizes
100 ug
£671.00
4821-MSM6-P1ABX-100UG
About this Product
- SKU:
- 4821-MSM6-P1ABX
- Additional Names:
- Homeobox protein NK-2 homolog B
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- rNX2/294
- Clonality:
- Monoclonal
- Extra Details:
- Expression of NKX2.2 has been found in neuroendocrine tumors of the gut; making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently; NKX2.2 protein was identified as a target of EWS-FLI-1; the fusion protein specific to Ewing sarcoma; and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma; with a sensitivity of 93% and a specificity of 89%; and aids in the differential diagnosis of small round cell tumors.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human NKX2.2 protein
- Isotype:
- IgG1
- Molecular Weight:
- 40-50kDa
- Research Area:
- Autophagy; Cardiovascular; Developmental Biology; Neural Stem Cells; Neuroscience; Stem Cell Differentiation
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=118834
