NGF-Receptor (p75) / CD271 (Soft Tissue Tumor Marker) Antibody
Product Sizes
100 ug
£671.00
4804-MSM1X-P1-100UG
About this Product
- SKU:
- 4804-MSM1X-P1
- Additional Names:
- Gp80-LNGFR | Low affinity neurotrophin receptor p75NTR | Low-affinity nerve growth factor receptor | p75 ICD
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry
- translate.label.attr.clone:
- SPM299
- Clonality:
- Monoclonal
- Extra Details:
- It recognizes a glycoprotein of 75kDa; identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region; a single transmembrane domain; and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development; differentiation; and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors; the high affinity p140 and low affinity p75.
- Host:
- Mouse
- Immunogen:
- NGFR from A875 melanoma cells
- Isotype:
- IgG1
- Molecular Weight:
- 75kDa
- Research Area:
- AKT Signaling; Mesenchymal Stem Cell Differentiation; Neuroscience; Nuclear Marker; Signal Transduction; Stem Cell Differentiation
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=118801
