NFIA / NF1A (Nuclear Factor 1A) (Transcription Factor) Antibody
Product Sizes
20 ug
£364.00
4774-MSM2-P0-20UG
About this Product
- SKU:
- 4774-MSM2-P0
- Additional Names:
- Class A basic helix-loop-helix protein 1 | NeuroD-related factor
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- PCRP-NFIA-2C6
- Clonality:
- Monoclonal
- Extra Details:
- NF-1; also designated CTF; consists of a family of CCAAT-box-binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA-binding domain; and activates transcription through a putatively novel; proline-rich; carboxy-terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes; including that of Ha-Ras; 伪-globin; HSP 70; GRP 78; Histone H1; myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human NFIA protein corresponding to protein domain
- Isotype:
- IgG2c
- Molecular Weight:
- 55kDa
- Research Area:
- Nuclear Marker; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=118775
