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Antibodies

NEUROD2 (Neurogenic Differentiation 2) (Transcription Factor) Antibody

Product Sizes
100 ug
£671.00
4761-MSM1-P1ABX-100UG
About this Product
SKU:
4761-MSM1-P1ABX
Additional Names:
Class A basic helix-loop-helix protein 1 | NeuroD-related factor
Application:
ELISA, Flow Cytometry, Immunofluorescence
translate.label.attr.clone:
PCRP-NEUROD2-1G1
Clonality:
Monoclonal
Extra Details:
Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes; both of which work together to activate DNA transcription. Class A proteins include the ubiquitously expressed E-box binding factors; namely E2A; ITF-2 and HEB; while class B proteins; such as MyoD; myogenin and Neuro D (尾2); are transiently expressed and exhibit a much more limited tissue distribution. Working in opposition to these positively acting factors are a specialized group of basic helix-loop-helix(bHLH) transcription factorsthat function as dominant negative regulators and are involved in cell lineage determination and differentiation. Neuro D2 (neurogenic differentiation 2); also known as NDRF; NEUROD2 or bHLHa1; is a 382 amino acid nuclear protein that contains one bHLH domain and functions to induce neurogenic differentiation; playing an important role in the maintenance and determination of cell fate.
Host:
Mouse
Immunogen:
Recombinant full-length human NEUROD2 protein
Isotype:
IgG2b
Molecular Weight:
~41kDa
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody