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Antibodies

ATM / ATM serine / threonine kinase Antibody

Product Sizes
100 ug
£671.00
472-MSM2-P1ABX-100UG
About this Product
SKU:
472-MSM2-P1ABX
Additional Names:
A-T mutated antibody; A-T mutated homolog antibody; AT mutated antibody; AT1 antibody; ATA antibody; Ataxia telangiectasia mutated antibody; Ataxia telangiectasia mutated gene antibody; Ataxia telangiectasia mutated homolog (human) antibody; Ataxia telangiectasia mutated homolog antibody; ATC antibody ATD antibody; ATDC antibody; ATE antibody ATM antibody; ATM serine/threonine kinase antibody; ATM_HUMAN antibody; DKFZp781A0353 antibody; MGC74674 antibody; OTTHUMP00000232981 antibody; Serine protein kinase ATM antibody; Serine-protein kinase ATM antibody; Serine/threonine-protein kinase ATM antibody; Tefu antibody TEL1 antibody; TEL1; telomere maintenance 1; homolog antibody; TELO1 antibody Telomere fusion protein antibody
Application:
Immunohistochemistry
translate.label.attr.clone:
ATM/9472
Clonality:
Monoclonal
Extra Details:
The phosphatidylinositol kinase (PIK) family members fall into two distinct subgroups. The first subgroup contains proteins such as the PI 3- and PI 4-kinases and the second group comprises the PIK-related kinases. The PIK-related kinases include Atm; DNA-PKCS and FRAP. These proteins have in common a region of homology at their carboxy-termini that is not present in the PI 3- and PI 4-kinases. The Atm gene is mutated in the autosomal recessive disorder ataxia telangiectasia (AT) that is characterized by cerebellar degeneration (ataxia) and the appearance of dilated blood vessels (telangiec-tases) in the conjunctivae of the eyes. AT cells are hypersensitive to ionizing radiation; impaired in mediating the inhibition of DNA synthesis and display delays in p53 induction.
Host:
Mouse
Immunogen:
Recombinant fragment (around aa1900-2500) of human ATM protein (exact sequence is proprietary)
Isotype:
IgG2b
Molecular Weight:
370kDa
Research Area:
Epigenetics
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody