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Antibodies

Recombinant CD56 / NCAM1 / NKH1 (Neuronal Cell Marker) Antibody

Product Sizes
100 ug
£671.00
4684-MSM34-P1ABX-100UG
About this Product
SKU:
4684-MSM34-P1ABX
Application:
Immunohistochemistry, Western Blot
translate.label.attr.clone:
rNCAM1/8758
Clonality:
Monoclonal
Extra Details:
This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule; which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule; the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma; medulloblastomas; astrocytomas; neuroblastomas; and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.
Host:
Mouse
Immunogen:
Recombinant fragment (around aa 700-858) of human NCAM1 protein (exact sequence is proprietary)
Isotype:
IgG2b
Molecular Weight:
145 and 125kDa|180
Research Area:
Cardiovascular; Cytokine Signaling; Developmental Biology; Hematopoietic Stem Cells; Immunology; Mesenchymal Stem Cell Differentiation; Neural Stem Cells; Neuroscience; Signal Transduction; Stem Cell
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody