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Antibodies

Recombinant MyoD1 (Rhabdomyosarcoma Marker) Antibody

Product Sizes
100 ug
£671.00
4654-RBM5-P1-100UG
About this Product
SKU:
4654-RBM5-P1
Additional Names:
Class C basic helix-loop-helix protein 1 | Myogenic factor 3
Application:
Immunohistochemistry, Western Blot
translate.label.attr.clone:
MYOD1/2075R
Clonality:
Monoclonal
Extra Details:
Recognizes a phospho-protein of 45kDa; identified as MyoD1. This MAb does not cross react with myogenin; Myf5; or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue; but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm s tumors. Weak cytoplasmic staining is observed in several non-muscle tissues; including glandular epithelium and also in rhabdomyosarcomas; neuroblastomas; Ewing s sarcomas and alveolar soft part sarcomas. Only nuclear staining should be considered as evidence of skeletal muscle differentiation.
Host:
Rabbit
Immunogen:
Recombinant human full-length MyoD1 protein
Isotype:
IgG
Molecular Weight:
45kDa
Research Area:
Cardiovascular; Developmental Biology; Mesenchymal Stem Cell Differentiation; Nuclear Marker
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody