MyoD1 (Rhabdomyosarcoma Marker) Antibody
Product Sizes
100 ug
£671.00
4654-MSM1-P1-100UG
About this Product
- SKU:
- 4654-MSM1-P1
- Additional Names:
- Class C basic helix-loop-helix protein 1 | Myogenic factor 3
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry
- translate.label.attr.clone:
- 5.8A
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a phosphor-protein of 45kDa; identified as MyoD1. The epitope of this MAb maps between amino acid 180-189 in the C-terminal of mouse MyoD1 protein. It does not cross react with myogenin; Myf5; or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue; but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm s tumors. Weak cytoplasmic staining is observed in several non-muscle tissues; including glandular epithelium and also in rhabdomyosarcomas; neuroblastomas; Ewing s sarcomas and alveolar soft part sarcomas.
- Host:
- Mouse
- Immunogen:
- Recombinant mouse MyoD1 protein
- Isotype:
- IgG1
- Molecular Weight:
- 45kDa
- Research Area:
- Cardiovascular; Developmental Biology; Mesenchymal Stem Cell Differentiation; Nuclear Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=118621
