Recombinant Smooth Muscle Myosin Heavy Chain (SM-MHC)(Leiomyosarcoma & Myoepithelial Cell Marker) Antibody
Product Sizes
100 ug
£671.00
4629-RBM10-P1ABX-100UG
About this Product
- SKU:
- 4629-RBM10-P1ABX
- Additional Names:
- Myosin heavy chain 11 | Myosin heavy chain; smooth muscle isoform | SMMHC
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- MYH11/7610R
- Clonality:
- Monoclonal
- Extra Details:
- Smooth Muscle Myosin; heavy chain (SMM-HC) is a cytoplasmic structural protein that is a major component of the contractile apparatus of the smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated; appearing early and is specific for smooth muscle development. SM-MHC stains the intact myoepithelial cell (MEC) layers present in benign and in situ malignant breast and bronchioloalveolar lesions and is therefore very helpful in distinguishing between benign and malignant tumors. The antibody reacts with smooth muscle cells and myoepithelial cells; but not with myofibroblasts. It is very helpful in distinguishing between benign sclerosing breast lesions and infiltrating carcinomas in difficult cases since it strongly stains the myoepithelial layer in the benign lesions while it is negative in the infiltrating carcinomas.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment (around aa1-200) of human MYH11 protein (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 227kDa
- Research Area:
- Cardiovascular; Developmental Biology; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=128749
