MYCN Antibody
Product Sizes
100 ug
£671.00
4613-MSM2-P1-100UG
About this Product
- SKU:
- 4613-MSM2-P1
- Additional Names:
- Class E basic helix-loop-helix protein 37
- Application:
- ELISA, Flow Cytometry
- translate.label.attr.clone:
- PCRP-MYCN-1A9
- Clonality:
- Monoclonal
- Extra Details:
- The v-Myc oncogene; initially identified in the MC29 avian retrovirus; causes myelocytomas; carcinomas; sarcomas and lymphomas; and belongs to a family of oncogenes conserved throughout evolution. In humans; the family consists of five genes: c-Myc; N-Myc; R-Myc; L-Myc and B-Myc. Amplification of the N-Myc gene has been found in human neuroblastomas and cell lines. Its amplification correlates well with the stage of neuroblastoma disease. Immunological studies have shown that the human N-Myc gene encodes a nuclear phosphoprotein that exhibits relatively short (30 min) half life in vivo. The prototype member of the family; c-Myc p67; binds DNA in a sequence-specific manner subsequent to dimerization with a second basic region helix-loop-helix leucine zipper motif protein; designated Max.
- Host:
- Mouse
- Immunogen:
- Recombinant protein domain (around aa335-463) of human MYCN protein
- Isotype:
- IgG1
- Molecular Weight:
- 49.56 kDa
- Research Area:
- Apoptosis; Autophagy; Cardiovascular; Neuroscience; Nuclear Marker; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=130868
