L-Myc / MYCL1 (Transcription Factor) Antibody
Product Sizes
100 ug
£671.00
4610-MSM1-P1-100UG
About this Product
- SKU:
- 4610-MSM1-P1
- Additional Names:
- Class E basic helix-loop-helix protein 38 | Protein L-Myc-1 | V-myc myelocytomatosis viral oncogene homolog
- Application:
- ELISA, Flow Cytometry, Immunofluorescence, Western Blot
- translate.label.attr.clone:
- PCRP-MYCL-2D5
- Clonality:
- Monoclonal
- Extra Details:
- Oncogene-encoded proteins c-Myc; N-Myc; and L-Myc function in cell proliferation; differentiation and neoplastic disease. Amplification of the c-Myc gene has been found in several types of human tumors; the N-Myc gene in neuroblastomas; and the L-Myc gene in human small cell lung carcinomas. c-Myc protein is a transcription factor localized to the nucleus of the cell. It seems to be involved in activating the transcription of growth-related genes. c-Myc binds to DNA during transcription as a heterodimeric complex with Max. c-Myc is phosphorylated in vitro by p44/42 MAP kinase at Ser62 and in vivo at both Thr58 and Ser62. Mutation of Thr58 and Ser62 to Ala inhibits the ability of c-Myc to activate transcription.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human MYCL protein
- Isotype:
- IgG2b
- Molecular Weight:
- 40.33kDa
- Research Area:
- Nuclear Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=118566
