c-Myc Oncoprotein Antibody
Product Sizes
20 ug
£364.00
4609-MSM2-P0-20UG
About this Product
- SKU:
- 4609-MSM2-P0
- Additional Names:
- Class E basic helix-loop-helix protein 39 | Proto-oncogene c-Myc | Transcription factor p64
- Application:
- Flow Cytometry, Immunofluorescence
- translate.label.attr.clone:
- CT14.G4
- Clonality:
- Monoclonal
- Extra Details:
- The c-Myc protein is a transcription factor; which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation; differentiation; apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3; cyclin dependent kinase; ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells; and which brought extensive attention in the development of new therapeutic approach for cancer treatment.
- Host:
- Mouse
- Immunogen:
- A synthetic peptide; corresponding to aa 408-439 (AEEQKLISEEDLLRKRREQLKHKLEQL-RNSCA) from C-terminus of human c-myc; coupled to KLH
- Isotype:
- IgG1
- Molecular Weight:
- 62-64kDa
- Research Area:
- Apoptosis; Autophagy; Bladder Cancer; Breast Cancer; Cancer; Cardiovascular; Colon Cancer; Cytokine Signaling; Developmental Biology; Hypoxia; Immunology; Infectious Disease; Lung Cancer; MAPK Signali
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=118533
