c-Myb Oncoprotein Antibody

Product Sizes

100 ug

£671.00

4602-MSM1-P1ABX-100UG

About this Product

SKU:: 4602-MSM1-P1ABX
Application:: ELISA
translate.label.attr.clone:: MYB286
Clonality:: Monoclonal
Extra Details:: The highly leukemogenic avian retrovirus E26 contains two oncogenes; v-Myb and v-Ets; which are expressed together as a fusion protein. The cellular homolog of v-Myb; designated c-Myb; encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel; leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially; but not exclusively; in immature hemopoietic cells and its expression decreases as cells differentiate.
Host:: Mouse
Immunogen:: A synthetic peptide; corresponding to aa 119-135 (RRKVEQEGYPQESSKAG) of c-myb onco protein; coupled to KLH
Isotype:: IgG1
Molecular Weight:: 75kDa
Research Area:: Cancer; Cardiovascular; Developmental Biology; Hypoxia; Nuclear Marker; Signal Transduction; Transcription Factors
Shipping Conditions:: Blue Ice
Storage Conditions:: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:: NeoBiotechnologies
Type:: Antibodies: Monoclonal Antibody

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