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Antibodies

MUC5AC (Mucin 5AC / Gastric Mucin) Antibody

Product Sizes
100 ug
£671.00
4586-MSM6-P1ABX-100UG
About this Product
SKU:
4586-MSM6-P1ABX
Additional Names:
Gastric mucin | Major airway glycoprotein | Mucin-5 subtype AC; tracheobronchial | Tracheobronchial mucin
Application:
Flow Cytometry, Immunofluorescence, Immunohistochemistry
translate.label.attr.clone:
MUC5AC/917
Clonality:
Monoclonal
Extra Details:
Mucin 5AC glycoprotein (MUC5AC) is a 641kDa glycoprotein belonging to the superfamily of mucins. Mucins are high molecular weight glycoproteins produced by epithelial cells and can be divided into two families; secretory mucins and membrane bound mucins. MUC5AC is a mucus-forming secreted mucin that is found in normal gastric and tracheo-bronchial mucosa but absent from normal colon. MUC5AC expression is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma; thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies; Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.
Host:
Mouse
Immunogen:
Recombinant fragment covering tandem repeats of human MUC5 protein (exact sequence is proprietary)
Isotype:
IgG1
Molecular Weight:
400-600kDa
Research Area:
Cardiovascular; Immunology; Infectious Disease
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody