MUC5AC (Mucin 5AC / Gastric Mucin) Antibody
Product Sizes
20 ug
£364.00
4586-MSM5-P0-20UG
About this Product
- SKU:
- 4586-MSM5-P0
- Additional Names:
- Gastric mucin | Major airway glycoprotein | Mucin-5 subtype AC; tracheobronchial | Tracheobronchial mucin
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry
- translate.label.attr.clone:
- CLH2
- Clonality:
- Monoclonal
- Extra Details:
- Mucin 5AC glycoprotein (MUC5AC) is a HMW glycoprotein belonging to the superfamily of mucins. Mucins are produced by epithelial cells and can be divided into two families; secretory mucins and membrane bound mucins. MUC5AC is a mucus-forming; secreted mucin that is found in normal gastric and tracheo-bronchial mucosa; but absent from normal colon. MUC5AC expression is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma; thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies; Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas. The antibody recognizes the sequence TTSTTSAP within the tandem repeat of MUC5AC. It further recognizes glycosylated as well as unglycosylated MUC5AC.
- Host:
- Mouse
- Immunogen:
- A synthetic peptide of human MUC5AC tandem repeat
- Isotype:
- IgG1
- Molecular Weight:
- >1|000kDa
- Research Area:
- Cardiovascular; Immunology; Infectious Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=118471
