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Antibodies

MUC5AC (Mucin 5AC / Gastric Mucin) Antibody

Product Sizes
20 ug
£364.00
4586-MSM1X-P0-20UG
About this Product
SKU:
4586-MSM1X-P0
Additional Names:
Gastric mucin | Major airway glycoprotein | Mucin-5 subtype AC; tracheobronchial | Tracheobronchial mucin
Application:
Flow Cytometry, Immunofluorescence, Immunohistochemistry
translate.label.attr.clone:
SPM297
Clonality:
Monoclonal
Extra Details:
This MAb recognizes the peptide core of gastric mucin M1 (1;000kDa) (recently identified as Mucin 5AC). Its epitope is destroyed by beta-mercaptoethanol and proteases but not by periodate treatment. Antibody to gastric mucin M1 reacts with the gastric epithelium of normal human gastrointestinal tract as well as with the precancerous and cancerous colon but not with normal adult colon. It also reacts with fetal colonic mucosa. Resurgence of gastric mucin reactivity during colonic carcinogenesis is due to re-expression of the peptide core of gastric (or fetal colonic) mucins.
Host:
Mouse
Immunogen:
M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient
Isotype:
IgG1
Molecular Weight:
>1|000kDa
Research Area:
Cardiovascular; Immunology; Infectious Disease
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody