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Antibodies

MUC5AC (Mucin 5AC / Gastric Mucin) Antibody

Product Sizes
100 ug
£671.00
4586-MSM1-B1X-100UG
About this Product
SKU:
4586-MSM1-B1X
Additional Names:
Gastric mucin | Major airway glycoprotein | Mucin-5 subtype AC; tracheobronchial | Tracheobronchial mucin
Application:
Flow Cytometry, Immunofluorescence, Immunohistochemistry
translate.label.attr.clone:
45M1
Clonality:
Monoclonal
Extra Details:
This MAb recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC). Its epitope is located in the C-terminal cysteine rich part of the peptide core of MUC5AC. Its epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma; thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies; Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.
Host:
Mouse
Immunogen:
M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient
Isotype:
IgG1
Molecular Weight:
400-600 kDa
Research Area:
Cardiovascular; Immunology; Infectious Disease
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody