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Antibodies

Recombinant MUC4 (Mucin 4 / Gastric Mucin) Antibody

Product Sizes
100 ug
£671.00
4585-RBM8-P1-100UG
About this Product
SKU:
4585-RBM8-P1
Additional Names:
Ascites sialoglycoprotein | Pancreatic adenocarcinoma mucin | Testis mucin | Tracheobronchial mucin
Application:
Immunohistochemistry
translate.label.attr.clone:
MUC4/8660R
Clonality:
Monoclonal
Extra Details:
The major constituents of mucus; the viscous secretion that covers epithelial surfaces such as those in the trachea; colon; and cervix; are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface; although secreted isoforms may exist. MUC-4 transcripts have been detected in normal respiratory epithelium and lung. MUC-4 is a very specific (100%) and sensitive (90%) marker of lung adenocarcinomas and is negative for mesotheliomas. Reportedly; MUC-4 expression in invasive ductal carcinoma of the pancreas is an independent factor for poor prognosis.
Host:
Rabbit
Immunogen:
Recombinant fragment (around aa 1729-1860) of human MUC4 protein (exact sequence is proprietary)
Isotype:
IgG
Molecular Weight:
235kDa
Research Area:
Cardiovascular; Immunology; Infectious Disease
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody