Recombinant MUC3 (Mucin 3) Antibody
Product Sizes
100 ug
£671.00
4584-RBM3-P1ABX-100UG
About this Product
- SKU:
- 4584-RBM3-P1ABX
- Additional Names:
- Intestinal mucin-3A
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- MUC3/2992R
- Clonality:
- Monoclonal
- Extra Details:
- It recognizes a protein of HMW; identified as mucin 3 glycoprotein (MUC3). Its epitope localizes between aa SITTTE. This MAb shows no cross-reaction with human milk fat globule membranes; MUC1; or MUC2. MUC3 is distributed in colon and rectum; and is also present to a lesser extent in breast; lung and salivary gland tissues. The Mucins are a family of highly glycosylated; secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) encoded by 60 base pairs (Mucin 1); 69 base pairs (Mucin 2) and 51 base pairs (Mucin 3). The number of repeats is highly polymorphic and varies among different alleles. Mucin 1 proteins are expressed as type I membrane proteins in addition to secreted forms. Mucin 1 is aberrantly expressed in epithelial tumors including breast carcinomas. Mucin 2 coats the epithelia of the intestines and airways and is associated with colonic tumors. Mucin 3 is a major component of various mucus gels and is broadly expressed in normal and tumor cells.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of 35 amino acids; SIB35 (C-HSTPSFTSSITTTETTSHSTPSFTSSITTTETTS); which contains two of the MUC3 tandem repeats; coupled to KLH
- Isotype:
- IgG
- Molecular Weight:
- 1100kDa
- Research Area:
- Immunology; Infectious Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=118416
