Recombinant MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) Antibody
Product Sizes
100 ug
£671.00
4582-RBM39-P1-100UG
About this Product
- SKU:
- 4582-RBM39-P1
- Additional Names:
- Breast carcinoma-associated antigen DF3 | Cancer antigen 15-3 | Carcinoma-associated mucin | Episialin | H23AG | Krebs von den Lungen-6 | PEMT | Peanut-reactive urinary mucin | Polymorphic epithelial mucin | Tumor-associated epithelial membrane antigen | Tumor-associated mucin
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- MSVA-672R
- Clonality:
- Monoclonal
- Extra Details:
- This MAb reacts with MUC1; a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. It is used as tracer agent in CA15.3 assays. The extracellular domain of MUC1 largely consists of a highly conserved; O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is up-regulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion. The dominant epitope of this MAb involves both amino acids as well as sugar moieties. Its epitope is destroyed by desialylation i.e. treatment with Neuraminidase.
- Host:
- Rabbit
- Immunogen:
- Recombinant human MUC1 protein
- Isotype:
- IgG
- Molecular Weight:
- 265-400kDa
- Research Area:
- Cytokine Signaling; Immunology; Infectious Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=147528
