Recombinant MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) Antibody
Product Sizes
100 ug
£671.00
4582-RBM24-P1-100UG
About this Product
- SKU:
- 4582-RBM24-P1
- Additional Names:
- Breast carcinoma-associated antigen DF3 | Cancer antigen 15-3 | Carcinoma-associated mucin | Episialin | H23AG | Krebs von den Lungen-6 | PEMT | Peanut-reactive urinary mucin | Polymorphic epithelial mucin | Tumor-associated epithelial membrane antigen | Tumor-associated mucin
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- MUC1/2980R
- Clonality:
- Monoclonal
- Extra Details:
- This MAb recognizes full-length MUC1 in a glycosylation-independent manner and can bind to the fully glycosylated protein.The dominant epitope of this MAb is APDTR in the VNTR region. It reacts with the core peptide of the MUC1 protein; which is a member of a family of mucin glycoproteins that are characterized by high carbohydrate content; O-linked oligosaccharides; high molecular weight (200kDa) and an amino acid composition rich in serine; threonine; proline and glycine. The core protein contains a domain of 20 amino-acid tandem repeats that functions as multiple epitopes for the MAb. Incomplete glycosylation of some tumor-associated mucins may lead to variable unmasking of the multiple peptide epitopes leading to the observed differences in staining intensity between normal and malignant tissues. This MAb reacts with both normal and malignant epithelia of various tissues including breast and colon.
- Host:
- Rabbit
- Immunogen:
- Recombinant full-length human MUC1 protein
- Isotype:
- IgG
- Molecular Weight:
- 265-400kDa
- Research Area:
- Cytokine Signaling; Immunology; Infectious Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=118382
