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Antibodies

Recombinant MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) Antibody

Product Sizes
100 ug
£671.00
4582-RBM21-P1-100UG
About this Product
SKU:
4582-RBM21-P1
Additional Names:
Breast carcinoma-associated antigen DF3 | Cancer antigen 15-3 | Carcinoma-associated mucin | Episialin | H23AG | Krebs von den Lungen-6 | PEMT | Peanut-reactive urinary mucin | Polymorphic epithelial mucin | Tumor-associated epithelial membrane antigen | Tumor-associated mucin
Application:
Immunohistochemistry
translate.label.attr.clone:
MUC1/2729R
Clonality:
Monoclonal
Extra Details:
In Western blotting; it recognizes proteins in MW range of 265-400kDa; identified as different glycoforms of EMA. This MAb reacts with the DTRP epitope in the tandem repeats. The alpha subunit has cell adhesive properties. It can act both as an adhesion and an anti-adhesion protein. EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain; which is involved in cell signaling; through phosphorylations and protein-protein interactions.In immunohistochemical assays; it superbly stains routine formalin/paraffin carcinoma tissues. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.
Host:
Rabbit
Immunogen:
Recombinant human MUC1 protein
Isotype:
IgG
Molecular Weight:
265-400kDa
Research Area:
Cancer; Cytokine Signaling; Immunology; Infectious Disease
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody