MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) Antibody
Product Sizes
100 ug
£671.00
4582-MSM2X-P1ABX-100UG
About this Product
- SKU:
- 4582-MSM2X-P1ABX
- Additional Names:
- Breast carcinoma-associated antigen DF3 | Cancer antigen 15-3 | Carcinoma-associated mucin | Episialin | H23AG | Krebs von den Lungen-6 | PEMT | Peanut-reactive urinary mucin | Polymorphic epithelial mucin | Tumor-associated epithelial membrane antigen | Tumor-associated mucin
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry
- translate.label.attr.clone:
- SPM533
- Clonality:
- Monoclonal
- Extra Details:
- In Western blotting; it recognizes proteins in MW range of 265-400kDa; identified as different glycoforms of EMA. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit and the C-terminal beta subunit. The alpha subunit has cell adhesive properties. It can act both as an adhesion and an anti-adhesion protein. EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain; which is involved in cell signaling; through phosphorylations and protein-protein interactions.In immunohistochemical assays; it superbly stains routine formalin/paraffin carcinomas. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.
- Host:
- Mouse
- Immunogen:
- Delipidated extract of human milk fat globule membranes
- Isotype:
- IgG2a
- Molecular Weight:
- 265-400kDa
- Research Area:
- Cancer; Cytokine Signaling; Immunology; Infectious Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=118326
