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Antibodies

Recombinant MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) Antibody

Product Sizes
20 ug
£364.00
4582-MSM28-P0-20UG
About this Product
SKU:
4582-MSM28-P0
Additional Names:
Breast carcinoma-associated antigen DF3 | Cancer antigen 15-3 | Carcinoma-associated mucin | Episialin | H23AG | Krebs von den Lungen-6 | PEMT | Peanut-reactive urinary mucin | Polymorphic epithelial mucin | Tumor-associated epithelial membrane antigen | Tumor-associated mucin
Application:
Immunohistochemistry, Western Blot
translate.label.attr.clone:
rMUC1/4418
Clonality:
Monoclonal
Extra Details:
In Western blotting; it recognizes proteins in MW range of 265-400kDa; identified as different glycoforms of EMA. EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack. In immunohistochemical assays; it superbly stains routine formalin/paraffin carcinomas. Anti-EMA antibody is a useful marker for staining many carcinomas. It stains normal and neoplastic cells from various tissues; including mammary epithelium; sweat glands and colorectal carcinoma. Hepatocellular carcinoma; adrenal carcinoma and embryonal carcinomas are consistently EMA negative; so keratin positivity with negative EMA favors one of these tumors. EMA is frequently positive in meningioma; which can be useful when distinguishing it from other intracranial neoplasms such as schwannomas. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.
Host:
Mouse
Immunogen:
Recombinant full-length human MUC1 protein
Isotype:
IgG2a
Molecular Weight:
265-400kDa
Research Area:
Cytokine Signaling; Immunology; Infectious Disease
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody