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Antibodies

MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) Antibody

Product Sizes
100 ug
£671.00
4582-MSM11-P1ABX-100UG
About this Product
SKU:
4582-MSM11-P1ABX
Additional Names:
Breast carcinoma-associated antigen DF3 | Cancer antigen 15-3 | Carcinoma-associated mucin | Episialin | H23AG | Krebs von den Lungen-6 | PEMT | Peanut-reactive urinary mucin | Polymorphic epithelial mucin | Tumor-associated epithelial membrane antigen | Tumor-associated mucin
Application:
ELISA, Western Blot
translate.label.attr.clone:
VU-2G7
Clonality:
Monoclonal
Extra Details:
MAb VU-2G7 reacts with MUC1; a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. The dominant epitope of VU-2G7 has not been established with 'epitope fingerprinting'. The'extra cellular domain of MUC1 largely consists of a highly conserved; O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is up regulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion.
Host:
Mouse
Immunogen:
Synthetic glycosylated MUC1 60mer tandem repeat NH2-(HGVTSAPDT(GalNAc)RPAPGSTAPPAHG)3- COOH; conjugated to bovine serum albumin
Isotype:
IgG1
Molecular Weight:
265-400kDa
Research Area:
Cancer; Cytokine Signaling; Immunology; Infectious Disease
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody