MTF1 Antibody
Product Sizes
100 ug
£671.00
4520-MSM1-P1ABX-100UG
About this Product
- SKU:
- 4520-MSM1-P1ABX
- Additional Names:
- MRE-binding transcription factor | Transcription factor MTF-1
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- MTF1/2649
- Clonality:
- Monoclonal
- Extra Details:
- The metal-responsive element (MRE)-binding transcription factor (MTF-1) stimulates the expression of metallothioneins in response to the exposure of cells to heavy metals. MTF-1 contains six zinc fingers in the DNA binding domain. The phosphorylation of MTF-1 in response to metal exposure appears to play a significant role in the ability of MTF-1 to activate metallothionein transcription. In addition to its role in metallothionein activation; MTF-1 is involved in a post-transcription regulatory complex for ribosomal protein S25. MTF-1; La and p53 inhibit the nuclear export of S25 mRNA in response to nutrient depravation. Furthermore; MTF-1 acts as a chromatin insulator on integrated transgenes in cultured cells to insulate active loci against chromatin silencing.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human MTF1 protein
- Isotype:
- IgG1
- Molecular Weight:
- 70kDa
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=118266
