Recombinant MSH2 (DNA Mismatch Repair Marker) Antibody
Product Sizes
20 ug
£431.00
4436-MSM85-P0-20UG
About this Product
- SKU:
- 4436-MSM85-P0
- Additional Names:
- MutS protein homolog 2
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- MSVA-902M
- Clonality:
- Monoclonal
- Extra Details:
- Mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC). Initially; inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes MutS and MutL were found at high frequency in HNPCC and were shown to be associated with microsatellite instability. The demonstration that 10 to 45% of pancreatic; gastric; breast; ovarian and small cell lung cancers also display microsatellite instability has been interpreted to suggest that DNA mismatch repair is not restricted to HNPCC tumors but is a common feature in tumor initiation or progression.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human MSH2 protein
- Isotype:
- IgG2a
- Molecular Weight:
- 100kDa
- Research Area:
- Colon Cancer; Infectious Disease; Nuclear Marker; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=147531
