Recombinant MMP9 (Matrix Metalloproteinase 9) Antibody
Product Sizes
20 ug
£364.00
4318-MSM6-P0-20UG
About this Product
- SKU:
- 4318-MSM6-P0
- Additional Names:
- 92 kDa gelatinase | 92 kDa type IV collagenase | Gelatinase B
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- rMMP9/1769
- Clonality:
- Monoclonal
- Extra Details:
- The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components; including collagen; gelatin; fibronectin; laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester; lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-9 (also designated 92 kDa type IV collagenase or gelatinase B) has been shown to degrade bone collagens in concert with MMP-1 (also designated interstitial collagenase; fibroblast collagenase or collagenase-1); and cysteine proteases and may play a role in bone osteoclastic resorption. MMP-1 is down-regulated by p53; and abnormality of p53 expression may contribute to joint degradation in rheumatoid arthritis by regulating MMP-1 expression.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human MMP-9 protein
- Isotype:
- IgG1
- Molecular Weight:
- 92kDa
- Research Area:
- Angiogenesis; Autophagy; BBB VCAM-1 Signaling; Bladder Cancer; Cardiovascular; Colon Cancer; Cytokine Signaling; Developmental Biology; Immunology; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=118174
