Recombinant MMP9 Matrix Metalloproteinase 9 (Papillary Thyroid Carcinoma Marker) Antibody
Product Sizes
20 ug
£364.00
4318-MSM12-P0-20UG
About this Product
- SKU:
- 4318-MSM12-P0
- Additional Names:
- 92 kDa gelatinase | 92 kDa type IV collagenase | Gelatinase B
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- r15W2
- Clonality:
- Monoclonal
- Extra Details:
- The matrix metalloproteinases (MMPs) are a family of zinc containing enzymes involved in the degradation of different components of the extracellular matrix and tissue remodelling. MMPs; which are expressed widely during growth and development; have been classified into collagenases; gelatinases and stromelysins; based on the in vitro substrate specificity. More recently several MMPs have been identified as membrane-type specific and matrilysin families. MMPs are multidomain proteins and are secreted as inactive precursors; which are activated by cleavage of an N-terminal pro-peptide. The major natural inhibitors of MMPs are tissue inhibitors of matrix metalloproteinases (TIMPs) which complex with MMPs and are involved in regulating the activity and activation of individual MMPs. MMP9 degrades collagen type IV; a major component of extracellular matrix. MMP9 is also reported to be observed immunohistochemically in normal kidney tubules; hepatocytes; spermatids; myocytes; stomach parietal cells; prostatic columnar epithelium and uterine cells.
- Host:
- Mouse
- Immunogen:
- Prokaryotic recombinant protein corresponding to a 134 amino acid portion of the C-terminal region of the mature human MMP9 molecule
- Isotype:
- IgG2a
- Molecular Weight:
- 92kDa
- Research Area:
- Angiogenesis; BBB VCAM-1 Signaling; Bladder Cancer; Cardiovascular; Colon Cancer; Cytokine Signaling; Developmental Biology; Immunology; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=141236
