MMP3 (Marker of Metastasis and Rheumatoid Arthritis) Antibody
Product Sizes
20 ug
£364.00
4314-MSM2-P0-20UG
About this Product
- SKU:
- 4314-MSM2-P0
- Additional Names:
- Matrix metalloproteinase-3 | Transin-1
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- MMP3/1730
- Clonality:
- Monoclonal
- Extra Details:
- The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components; including collagen; gelatin; fibronectin; laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester; lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3; MMP-10 and MMP-11 (also designated stromelysin-1; 2 and 3; respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine; and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human MMP3 protein
- Isotype:
- IgG1
- Molecular Weight:
- 57kDa
- Research Area:
- Angiogenesis; Cardiovascular; Cytokine Signaling; Immunology; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=118146
