NR3C2 Antibody
Product Sizes
100 ug
£671.00
4306-MSM2-P1ABX-100UG
About this Product
- SKU:
- 4306-MSM2-P1ABX
- Additional Names:
- Nuclear receptor subfamily 3 group C member 2
- Application:
- Flow Cytometry
- translate.label.attr.clone:
- PCRP-NR3C2-1E3
- Clonality:
- Monoclonal
- Extra Details:
- Mineralocorticoid hormones are primarily found in epithelial tissues where they function as regulators of Na+; K+ and H+ ion transport. Aldosterone is a mineralocorticoid that has been shown to regulate electrolyte excretion and intravascular volume and is therefore involved in blood pressure regulation. Mineralocorticoid receptor (MCR or MR) is a member of the steroid/thyroid/ retinoic nuclear hormone receptor superfamily that has been shown to activate gene transcription in response to aldosterone binding. Regulation of the mineralocorticoid receptors occurs through either receptor downregulation (negative autoregulation) or hormone-mediated upregulation (positive autoregulation). MCR association with HSP 90 appears to be required for hormone binding to MCR and subsequent MCR activation.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa601-673) of human NR3C2 protein
- Isotype:
- IgG1
- Molecular Weight:
- 107kDa
- Research Area:
- Cardiovascular; Nuclear Marker; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=134829
