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Antibodies

Ki-67 (Proliferating Cell Marker) Antibody

Product Sizes
100 ug
£671.00
4288-MSM2-P1-100UG
About this Product
SKU:
4288-MSM2-P1
Additional Names:
Antigen identified by monoclonal antibody Ki-67
Application:
Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
translate.label.attr.clone:
MKI67/2462
Clonality:
Monoclonal
Extra Details:
Ki-67 antigen is a nuclear; non-histone protein that is present in all stages of the cell cycle except G0. This characteristic makes Ki-67 an excellent marker for proliferating cells and is commonly used as one of the prognostic factors in cancer studies. A correlation has been demonstrated between Ki-67 index and the histo-pathological grade of neoplasms. Assessment of Ki-67 expression in renal and ureter tumors shows a correlation between tumor proliferation and disease progression; thus making it possible to differentiate high-risk patients. Ki-67 expression may also prove to be important for distinguishing between malignant and benign peripheral nerve sheath tumors. Ki-67 labeling index has been shown to be a prognostic marker in a number of neoplasms including grade II astrocytoma; oligodendroglioma; colon carcinoma; and breast carcinoma. In general; Ki-67 is a good marker of proliferating cell populations.
Host:
Mouse
Immunogen:
Recombinant human Ki67 protein fragment (around aa 2293-2478) (exact sequence is proprietary)
Isotype:
IgG2b
Molecular Weight:
345kDa and 395kDa
Research Area:
Neuroscience; Nuclear Marker
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody