MIF (Macrophage Migration Inhibitory Factor) Antibody
Product Sizes
100 ug
£671.00
4282-MSM2-P1ABX-100UG
About this Product
- SKU:
- 4282-MSM2-P1ABX
- Additional Names:
- Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | Phenylpyruvate tautomerase
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- MIF/3489
- Clonality:
- Monoclonal
- Extra Details:
- Macrophage migration inhibitory factor; known as MIF or glycosylationinhibiting factor; is a secreted; homotrimeric; pro-inflammatory cytokine that modulates macrophage and T cell function and is an important regulator of host response to infection. MIF is expressed at sites of inflammation; which suggests that it plays a role in regulating macrophage function in host defense. MIF is produced by the pituitary gland and is found in monocytes; macrophages; differentiating immunological cells in the eye lens and brain; and fibroblasts. Elevated levels of MIF protein are detected in the plasma of patients with severe sepsis or septic shock; a condition where MIF influences endotoxic shock by enhancing the production of other inflammatory cytokines including tumor necrosis factor 伪 (TNF伪); interleukin-1 (IL-1) and interferon-纬 (IFN-纬). MIF promotes the systemic inflammatory response by counter-regulating glucocorticoid-mediated inhibition of immune-cell activation and proinflammatory cytokine production. MIF may mediate tissue destruction through the induction of proteinases.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human MIF protein (exact sequence is proprietary)
- Isotype:
- IgG2a
- Molecular Weight:
- ~13kDa
- Research Area:
- Cardiovascular; Cytokine Signaling; Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=117968
