CD99 / MIC2 (Ewing's Sarcoma Marker) Antibody
Product Sizes
20 ug
£364.00
4267-RBP6-P0-20UG
About this Product
- SKU:
- 4267-RBP6-P0
- Additional Names:
- 12E7 | E2 antigen | Protein MIC2 | T-cell surface glycoprotein E2
- Application:
- Immunohistochemistry
- Clonality:
- Polyclonal
- Extra Details:
- Recognizes a sialoglycoprotein of 27-32kDa; identified as CD99; or MIC2 gene product; or E2 antigen. MIC2 gene is located in the pseudo-autosomal region of the human X and Y chromosome. MIC2 gene encodes two distinct proteins; which are produced by alternative splicing of the CD99 gene transcript and are identified as bands of 30 and 32kDa (p30/32).Although its function is not fully understood; CD99 is implicated in various cellular processes including homotypic aggregation of T cells; upregulation of T cell receptor and MHS molecules; apoptosis of immature thymocytes and leukocyte diapedesis.CD99 is expressed on the cell membrane of some lymphocytes; cortical thymocytes; and granulosa cells of the ovary. Most pancreatic islet cells; Sertoli cells of the testis; and some endothelial cells express this antigen. Mature granulocytes express very little or no CD99. MIC2 is strongly expressed on Ewing's sarcoma cells and primitive peripheral neuroectodermal tumors.
- Host:
- Rabbit
- Immunogen:
- Recombinant human MIC2 protein
- Isotype:
- IgG
- Molecular Weight:
- 27-32kDa
- Research Area:
- Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=117966
