Recombinant CD99 / MIC2 (Ewing s Sarcoma Marker) Antibody
Product Sizes
100 ug
£671.00
4267-RBM8-P1ABX-100UG
About this Product
- SKU:
- 4267-RBM8-P1ABX
- Additional Names:
- 12E7 | E2 antigen | Protein MIC2 | T-cell surface glycoprotein E2
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- MIC2/3478R
- Clonality:
- Monoclonal
- Extra Details:
- CD99 is a type I transmembrane glycoprotein encoded by the CD99 gene and the functions of CD99 in cells in which CD99 was highly expressed have been studied and they were as follows: cell death of thymocytes and T lymphocytes; migration through monocyte endothelial junctions by adhesion and diapedesis; cell-cell adhesion in lymphocytes; maintenance of cellular morphology in Hodgkin and Reed/Sternberg cells; and recruitment of T cells.CD99 expression has been reported in many cell types; such as hematopoietic cells; endothelial cells; central nervous system ependymal cells; thymocytes; granular cells of the ovary; Sertoli cells; and pancreatic islet cells. And in tumors it expressed by virtually almost all Ewing s sarcoma and primitive peripheral neuroectodermal tumors (ES/PNET) and demonstrates strong and diffuse membranous staining. Other tumors that may show CD99 expression include neuroendocrine carcinomas; mesenchymal chondrosarcomas; solitary fibrous tumors; synovial sarcomas; vascular tumors; small round blue cell tumors; lymphoblastic lymphoma; acute myeloid leukemia; and myeloid sarcoma. Studies have shown that CD99 may be a sensitive marker for Ewing s sarcoma and peripheral neuroectodermal tumors.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide corresponding to CD99 residues within aa85 C terminal of CD99 was used as an immunogen
- Isotype:
- IgG
- Molecular Weight:
- 27-32kDa
- Research Area:
- Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=117965
