Recombinant MDM2 Antibody
Product Sizes
100 ug
£671.00
4193-RBM7-P1-100UG
About this Product
- SKU:
- 4193-RBM7-P1
- Additional Names:
- Double minute 2 protein | Oncoprotein Mdm2 | RING-type E3 ubiquitin transferase Mdm2 | p53-binding protein Mdm2
- Application:
- ELISA
- translate.label.attr.clone:
- MDM2/7061R
- Clonality:
- Monoclonal
- Extra Details:
- MDM2 is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53. It can promote tumor formation by targeting tumor suppressor proteins; such as p53; for proteasomal degradation. Overexpression of MDM2 can result in excessive inactivation of tumor protein p53; diminishing its tumor suppressor function. This protein also affects the cell cycle; apoptosis; and tumorigenesis through interactions with other proteins; including retinoblastoma 1 and ribosomal protein L5. Overexpression of MDM2 protein is detected in a variety of cancers.
- Host:
- Rabbit
- Immunogen:
- Recombinant human MDM2 protein fragment (around aa 126-254) (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- ~90kDa
- Research Area:
- AKT Signaling; Bladder Cancer; Cardiovascular; Infectious Disease; Nuclear Marker; Signal Transduction; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=117847
