CD46 (Membrane Cofactor Protein) Antibody
Product Sizes
20 ug
£364.00
4179-MSM2-P0-20UG
About this Product
- SKU:
- 4179-MSM2-P0
- Additional Names:
- TLX | Trophoblast leukocyte common antigen
- Application:
- Flow Cytometry, Immunofluorescence
- translate.label.attr.clone:
- 169-1-E4.3
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 52kDa-58kDa; identified as CD46 (also known as membrane cofactor protein; MCP). Its epitope is located on the four immunogenic short consensus repeat (SCR) domains at N-terminus of the protein. CD46 exists as many isoforms in a variety of tissues. It is strongly expressed on salivary gland ducts and kidney ducts; moderately on lymphocytes and endothelium; and weakly on interstitial tissues and muscle cells; but not on erythrocytes. CD46 functions as a C3b/C4b-binding glycoprotein that inhibits complement activation on host cells. It also serves as a measles virus receptor; an adherence factor for group Streptococcus pyogenes; and a cellular pilus receptor for pathogenic Neisseria.
- Host:
- Mouse
- Immunogen:
- Stimulated human leukocytes
- Isotype:
- IgG2a
- Molecular Weight:
- 52-58kDa
- Research Area:
- Complement System; Endothelial Cell Marker; Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=117841
