MCM6 (Proliferation Marker) Antibody
Product Sizes
100 ug
£671.00
4175-MSM1-P1-100UG
About this Product
- SKU:
- 4175-MSM1-P1
- Additional Names:
- p105MCM
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- MCM6/2999
- Clonality:
- Monoclonal
- Extra Details:
- The mini-chromosome maintenance (MCM) family of proteins; including MCM2; MCM3; MCM6 (Cdc21); MCM5 (Cdc46); MCM6 (Mis5) and MCM7 (Cdc47); are regulators of DNA replication that act to ensure replication occurs only once in the cell cycle. Expression of MCM proteins increases during cell growth; peaking at G1/S phase. The MCM proteins each contain an ATP-binding motif; which is predicted to mediate ATP-dependent opening of double-stranded DNA. MCM proteins are regulated by E2F transcription factors; which induce MCM expression; and by protein kinases; which interact with MCM proteins to maintain the post-replicative state of the cell. MCM2/MCM6 complexes function as substrates for Cdc2/cyclin B in vitro.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 228-368) of human MCM6 protein (exact sequence is proprietary)
- Isotype:
- IgG2b
- Molecular Weight:
- 105kDa
- Research Area:
- Nuclear Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=117785
