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Antibodies

Recombinant MCM3 (Proliferation Marker) Antibody

Product Sizes
100 ug
£671.00
4172-RBM6-P1-100UG
About this Product
SKU:
4172-RBM6-P1
Additional Names:
DNA polymerase alpha holoenzyme-associated protein P1 | P1-MCM3 | RLF subunit beta | p102
Application:
Immunohistochemistry
translate.label.attr.clone:
MCM3/8972R
Clonality:
Monoclonal
Extra Details:
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites; however; are likely to contribute differentially to the complex helicase activity. Required for DNA replication and cell proliferation.
Host:
Rabbit
Immunogen:
Recombinant fragment (aa 650-750) of human MCM3 protein (exact sequence is proprietary)
Isotype:
IgG
Molecular Weight:
115kDa
Research Area:
Nuclear Marker
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody