MCM2 (ProliferationMarker) Antibody
Product Sizes
100 ug
£671.00
4171-MSM1-P1ABX-100UG
About this Product
- SKU:
- 4171-MSM1-P1ABX
- Additional Names:
- Minichromosome maintenance protein 2 homolog | Nuclear protein BM28
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- MCM2/3678
- Clonality:
- Monoclonal
- Extra Details:
- The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array; containing more than 19;000; full-length human proteins. MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2; 4 and 6 proteins possesses DNA helicase activity; and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase; CDK4; is found to associate with this protein; and may regulate the binding of this protein with the tumor suppressor protein RB1/RB.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (aa 650-750) of human MCM2 protein (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 102kDa
- Research Area:
- Nuclear Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=117784
