MCAM (Melanoma Cell Adhesion Molecule) / MUC18 / CD146 Antibody
Product Sizes
100 ug
£671.00
4162-MSM8-P1-100UG
About this Product
- SKU:
- 4162-MSM8-P1
- Additional Names:
- Cell surface glycoprotein P1H12 | Melanoma cell adhesion molecule | Melanoma-associated antigen A32 | Melanoma-associated antigen MUC18 | S-endo 1 endothelial-associated antigen
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- MCAM/3048
- Clonality:
- Monoclonal
- Extra Details:
- The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein; also designated MCAM; MUC 18 or CD146; that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage; but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
- Host:
- Mouse
- Immunogen:
- Recombinant human MCAM protein fragment (around aa226-374) (exact sequence is proprietary)
- Isotype:
- IgG2b
- Molecular Weight:
- 130kDa
- Research Area:
- Endothelial Cell Marker; Mesenchymal Stem Cell Differentiation; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=117782
