MBD1 (Methyl-CpG Binding Domain Protein 1) Antibody
Product Sizes
20 ug
£364.00
4152-MSM1-P0-20UG
About this Product
- SKU:
- 4152-MSM1-P0
- Additional Names:
- CXXC-type zinc finger protein 3 | Methyl-CpG-binding protein MBD1 | Protein containing methyl-CpG-binding domain 1
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- CPTC-MBD1-1
- Clonality:
- Monoclonal
- Extra Details:
- DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2; MBD1; MBD2; MBD3; and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins; with the exception of MBD3; is capable of binding specifically to methylated DNA. MECP2; MBD1 and MBD2 can also repress transcription from methylated gene promoters. MBD1 has also been predicted to be involved in the development and progression of tumors; and it has been shown that MBD1 is significantly upregulated in pancreatic cancer tissues when compared with surrounding normal tissues. Furthermore; MBD1 may serve as a potential therapeutic target for pancreatic cancer.
- Host:
- Mouse
- Immunogen:
- Recombinant human MBD1 protein
- Isotype:
- IgG2
- Molecular Weight:
- ~80kDa
- Research Area:
- Nuclear Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=117721
