MAGE-1 (Target for Cancer Immunotherapy) Antibody
Product Sizes
100 ug
£671.00
4100-MSM1-P1-100UG
About this Product
- SKU:
- 4100-MSM1-P1
- Additional Names:
- Antigen MZ2-E | Cancer/testis antigen 1.1 | MAGE-1 antigen
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- MA454
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 42-46kDa; identified as MAGE-1. This MAb does not cross-react with MAGE-2; -3; -4; -6 -9; -10; -or -12 protein. Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous; tumor directed and specific; cytolytic; CD8+ T lymphocyte clones (CTL). The MAGE family of genes codes an important group of antigens. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma; brain tumors of glial origin; neuroblastoma; non-small cell lung cancer; breast; gastric; colorectal; ovarian; renal cell carcinomas) and not on normal tissues; the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human MAGE-A1 protein
- Isotype:
- IgG1
- Molecular Weight:
- 42-46kDa
- Research Area:
- Immuno Oncology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=117692
