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Antibodies

SMAD3 Antibody

Product Sizes
100 ug
£671.00
4088-MSM1-P1ABX-100UG
About this Product
SKU:
4088-MSM1-P1ABX
Additional Names:
JV15-2 | SMAD family member 3
Application:
Flow Cytometry, Immunofluorescence
translate.label.attr.clone:
PCRP-SMAD3-1A2
Clonality:
Monoclonal
Extra Details:
Smad proteins; the mammalian homologs of the Drosophila mothers against dpp (Mad) have been implicated as downstream effectors of TGF尾/BMP signaling. Smad1 (also designated Madr1 or JV4-1); Smad5 and mammalian Smad8 (also designated Smad9 or MadH6) are effectors of BMP-2 and BMP-4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGF尾 and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGF尾 signaling by interfering with TGF尾-mediated phosphorylation of other Smad family members.
Host:
Mouse
Immunogen:
Recombinant full-length human SMAD3 protein
Isotype:
IgG1
Molecular Weight:
54kDa
Research Area:
Cardiovascular; Colon Cancer; Cytokine Signaling; Developmental Biology; Immunology; Infectious Disease; Neuroinflammation; Signal Transduction; Transcription Factors
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody