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Antibodies

Ep-CAM / CD326 (Extracellular Domain) (Epithelial Marker) Antibody

Product Sizes
0.1 ml
£364.00
4072-MSM4-CS0-0.1ML
About this Product
SKU:
4072-MSM4-CS0
Additional Names:
Adenocarcinoma-associated antigen | Cell surface glycoprotein Trop-1 | Epithelial cell surface antigen | Epithelial glycoprotein | Epithelial glycoprotein 314 | KS 1/4 antigen | KSA | Major gastrointestinal tumor-associated protein GA733-2 | Tumor-associated calcium signal transducer 1
Application:
Flow Cytometry, Immunohistochemistry
translate.label.attr.clone:
Ber-EP4
Clonality:
Monoclonal
Extra Details:
Recognizes a 40-43kDa transmembrane epithelial glycoprotein; identified as epithelial specific antigen (ESA); or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas with the exception of adult squamous epithelium; hepatocytes and gastric epithelial cells. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. It is also useful in distinguishing serous carcinomas of the ovary from mesothelioma. It has been reported that this epithelial antigen plays an important role as a tumor-cell marker in lymph nodes from patients with esophageal carcinoma otherwise classified as node-negative. Epithelial antigen has also been suggested as a discriminator between basal cell and baso-squamous carcinomas; and squamous cell carcinoma of the skin.
Host:
Mouse
Immunogen:
Human breast cancer MCF-7 cells
Isotype:
IgG1
Molecular Weight:
40-43kDa
Research Area:
Stem Cell Differentiation
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody