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Antibodies

Lactotransferrin / Lactoferrin / LTF Antibody

Product Sizes
100 ug
£671.00
4057-MSM12-P1ABX-100UG
About this Product
SKU:
4057-MSM12-P1ABX
Additional Names:
Growth-inhibiting protein 12 | Talalactoferrin
Application:
Flow Cytometry, Immunofluorescence, Immunohistochemistry
translate.label.attr.clone:
LTF/4082
Clonality:
Monoclonal
Extra Details:
Ferritin and transferrins manage necessary iron-binding functions for iron metabolism. Transferrins comprise a class of single-chain; two-sited; metal-binding proteins expressed throughout the fluid and cells of vertebrates. The three major types of transferrin include serotransferrin; lactotransferrin (lactoferrin) and ovotransferrin. Lactoferrin is found in milk; tears and leukocytes. It degrades an IgA1protease secreted by Haemophilus influenzae and; consequently; allows the human IgA1antibody to effectively abolish Haemophilus influenzae colonization. Lactoferrin also attenuates the pathogenic potential of Haemophilus influenzae by proteolytic degradation of the Hap adhesin. While lactoferrin may aid in the transmission of human T cell leukemiavirus type 1; it inhibits HIV-1 replication at the level of viral fusion and entry into cells. The inhibitory effects of lactoferrin on mixed lymphocyte reactions suggest that it may have the ability to sense the activation status of lymphocytes.
Host:
Mouse
Immunogen:
Recombinant fragment (around aa614-645) of human Lactotransferrin protein (exact sequence is proprietary)
Isotype:
IgG2b
Molecular Weight:
78kDa
Research Area:
Immunology; Infectious Disease
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody