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Antibodies

Luteinizing Hormone / Choriogonadotropin Receptor (LHCGR) Antibody

Product Sizes
100 ug
£671.00
3973-MSM3-P1-100UG
About this Product
SKU:
3973-MSM3-P1
Additional Names:
Luteinizing hormone receptor
Application:
ELISA, Flow Cytometry, Western Blot
translate.label.attr.clone:
LHCGR/1417
Clonality:
Monoclonal
Extra Details:
Recognizes a protein of 78-85kDa; which is identified as Luteinizing hormone / choriogonadotropin receptor. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone / choriogonadotropin receptor (LHCGR) as a seven transmembrane; G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women.
Host:
Mouse
Immunogen:
Recombinant fragment (around aa 70-410) of human LHCGR protein (exact sequence is proprietary)
Isotype:
IgG1
Molecular Weight:
78-85kDa
Research Area:
Signal Transduction
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody