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Antibodies

Galectin-1 / Human Placental Lactogen (hPL) Antibody

Product Sizes
100 ug
£671.00
3956-MSM1-P1ABX-100UG
About this Product
SKU:
3956-MSM1-P1ABX
Additional Names:
14 kDa laminin-binding protein | 14 kDa lectin | Beta-galactoside-binding lectin L-14-I | Galaptin | HBL | HPL | Lactose-binding lectin 1 | Lectin galactoside-binding soluble 1 | Putative MAPK-activating protein PM12 | S-Lac lectin 1
Application:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
translate.label.attr.clone:
GAL1/1831
Clonality:
Monoclonal
Extra Details:
Galectin-1 is a member of the beta-galactoside-binding family and is a dimeric protein of 14kD participating in a variety of normal and pathological processes; including cancer progression. Galectin-1 can affect the proliferation of normal and malignant cells. Inhibition of cell growth is observed in a lactose-dependent manner as lower concentrations of the lectin stimulate cell proliferation. Galectin-1 may also be implicated in the induction of apoptosis of activated T cells through the binding of exogenous galectin-1 to CD45 molecules present on the surface of lymphocytes. Galectin-1; reported to be present either at the surface of cancer cells or accumulated around these cells could act as an immunological shield to protect against a T cell immune response and provide an advantage for survival.
Host:
Mouse
Immunogen:
Recombinant fragment (around aa12-108) of human Galectin-1 protein (exact sequence is proprietary)
Isotype:
IgG1
Molecular Weight:
14kDa
Research Area:
Apoptosis; Autophagy; Cardiovascular; Immuno Oncology
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody