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Antibodies

Recombinant Laminin Receptor/ RPSA (Marker of Metastatic Potential) Antibody

Product Sizes
100 ug
£671.00
3921-MSM3-P1-100UG
About this Product
SKU:
3921-MSM3-P1
Additional Names:
37 kDa laminin receptor precursor | 37/67 kDa laminin receptor | 67 kDa laminin receptor | Colon carcinoma laminin-binding protein | Laminin receptor 1 | Laminin-binding protein precursor p40 | Multidrug resistance-associated protein MGr1-Ag | NEM/1CHD4 | Small ribosomal subunit protein uS2
Application:
Immunohistochemistry
translate.label.attr.clone:
rRPSA/6333
Clonality:
Monoclonal
Extra Details:
Laminins; a family of extracellular matrix glycoproteins; are the major non-collagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion; differentiation; migration; signaling; neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family; as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity; non-integrin family; laminin receptor 1. Reportedly; level of laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also; there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype.
Host:
Mouse
Immunogen:
Recombinant full-length human RPSA protein
Isotype:
IgG1
Molecular Weight:
37-67kDa
Research Area:
Developmental Biology; Infectious Disease
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody